Grey's Anatomy Season 10, Episode 21: Change of Heart

1

Seal Our Fate

The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already short handed ER to spring into action. Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona’s infidelity, and Richard’s life is in extreme danger.

43 min

2

I Want You with Me

Callie makes a decision about her relationship; the doctors receive devastating news.

43 min

3

Everybody's Crying Mercy

Derek and Meredith adjust to life at home with their newborn; Arizona tries to repair her marriage; Jackson and Owen clash over financial issues.

43 min

4

Puttin' on the Ritz

The doctors of Grey Sloan Memorial throw a fundraising gala which turns wildly competitive after Jackson makes a rash promise. Back at the hospital, Bailey’s patience is tested when she has to deal with several extremely difficult patients. Meanwhile, Shane and Stephanie handle an incredibly busy ER by themselves and Alex reveals an emotional secret to Jo.

43 min

5

I Bet It Stung

Meredith struggles to balance her roles as a surgeon and a mother when she returns to work; Stephanie tries to impress Jackson's mother; Jo becomes overly involved with a patient.

43 min

6

Map of You

Derek and Callie work on a brain mapping project, Richard encourages the interns to use his physical condition as a learning tool and after a discussion with Callie, Meredith considers continuing her mother’s research. Meanwhile, Shane continues to feel guilty about Heather’s death.

43 min

7

Thriller

Costumed patients create a challenge for the doctors; Derek and Ben work on a new surgical technique; Richard asks a resident to perform his next surgery, angering Bailey.

43 min

8

Two Against One

A betrayal intensifies the issues between Cristina and Meredith; Matthew and April make a decision about their relationship; Bailey faces difficulties with Ben's return.

43 min

9

Sorry Seems to Be the Hardest Word

When an unexpected malpractice suit turns Callie's world upside down, her supportive father arrives and shares an interesting secret with her. Meanwhile, through flashbacks, we learn some surprising details about Callie and Arizona's marriage.

43 min

10

Somebody That I Used To Know

Ben worries that a casual conversation with Derek could potentially cause issues for Bailey, Cristina turns to Shane as tension grows with Meredith, and April's upcoming wedding makes for an uncomfortable situation between Jackson and Stephanie. Meanwhile, Meredith plans a Thanksgiving dinner at her house.

43 min

11

Man on the Moon

April’s sisters arrive to help celebrate April’s upcoming nuptials and quickly get on her nerves. Matthew and Jackson are forced to work together when they witness a terrible accident, Callie and Arizona work hard to reestablish their relationship and Cristina is pressured to live stream an upcoming surgery. Meanwhile, a familiar face returns to the hospital.

43 min

12

Get Up, Stand Up

On the day of April's wedding, the Grey Sloan Memorial doctors are all preoccupied with their own drama. Meredith and Cristina continue to argue about their research and careers, Bailey comes clean to Ben about her feelings regarding him moving back to Seattle, and Shane puts himself in a risky situation. Meanwhile, Derek gets a phone call that will change his life.

43 min

13

Take It Back

The doctors are faced with the consequences of the events at April's wedding. Alex reacts to the news about his father. Callie and Arizona make a decision about their relationship.

43 min

14

You've Got to Hide Your Love Away

After an anonymous complaint is issued by one of their own, the hospital implements a non-fraternizing policy causing the couples to panic. Meanwhile, Emma and Owen talk about the future, Cristina and Meredith enjoy a little girl time, and Richard enlists the residents to help research a rare cancer case.

43 min

15

Throwing it All Away

Arizona has a bad day which escalates when she advises one of Callie's patients on a potential double amputation. Derek goes back on a promise to Callie, and Jo and Stephanie come across an abandoned baby outside the hospital. Meanwhile, the doctors deal with the repercussions of the non-fraternization rule, which include meetings with HR and one doctor's suspension.

43 min

16

We Gotta Get Out of This Place

It's Richard's birthday and Bailey invites him to scrub in on the case of a lifetime. Meredith hires a research assistant to help with her portal vein project. A scorned Callie gives Derek quite the shock. Meanwhile, Shane helps screen candidates for Cristina's clinical trial and meets a young expectant mother who needs his help.

43 min

17

Do You Know?

Cristina imagines the two routes her life can take based on one decision she makes. Meanwhile one of the hospital’s patients decides whether or not to live.

43 min

18

You Be Illin'

The hospital gets inundated with flu infected patients, which causes the doctors to slowly fall ill one by one. Derek must fight off the sickness as he prepares to give a speech on brain mapping and the residents place bets on who will fall ill first. Meanwhile, a new doctor at the hospital gives Alex a glimpse into an alternate form of medical practice.

43 min

19

I'm Winning

Cristina won't let herself get excited when she is nominated for a Harper Avery award; Alex thinks about making a change; Callie and Derek work with a machine that recognizes emotions.

43 min

20

Go It Alone

Cristina enlists Meredith to help her prepare an acceptance speech for her possible Harper Avery win and while Owen offers to attend the ceremony with her, she insists on going alone. Meanwhile, Derek feels overwhelmed between his responsibilities at home and at the hospital. April and Jackson come to a disagreement on children and religion, and Callie and Arizona try to reconnect in their marriage.

43 min

21

Change of Heart

Jackson is given the daunting task of delivering disappointing news to the doctors. Meanwhile, Derek's sister Amelia drops by for a surprise visit, Richard surprises Catherine in Boston and when Bailey gets frustrated by the slow pace of her research, she makes a risky decision.

43 min

22

We Are Never Ever Getting Back Together

Cristina considers her future at the hospital; Amelia and Derek collaborate on a tough surgery involving conjoined twins; Jo takes on too many cases at once; Stephanie stumbles on the truth about Bailey's case.

43 min

23

Everything I Try to Do, Nothing Seems to Turn Out Right

With Derek away, Meredith spends time with Amelia and finds out her true feelings about her time in Seattle. Bailey deals with the ramifications of her actions and Callie receives devastating news. Meanwhile, the residents panic after hearing that one of them will be fired

43 min

24

Fear (of the Unknown)

The doctors of Grey Sloan Memorial Hospital bid an emotional farewell to the beloved Cristina Yang. A possible act of terrorism rocks Seattle and causes chaos at the hospital. Meanwhile, Meredith makes a life changing decision and one doctor receives shocking news.

43 min