Watch What Happens Live with Andy Cohen Season 22, Episode 50: Debra Messing, Ellen Pompeo

Diana Cruz, Danni Warren

Andy Cohen interviews Diana Cruz and Danni Warren.

21 min

Erika Jayne, Racquel Chevremont

Andy Cohen interviews Erika Jayne & Racquel Chevremont.

21 min

Dorinda Medley, Whitney Rose

Andy Cohen interviews Dorinda Medley and Whitney Rose.

21 min

Glenn Close

Andy Cohen interviews Glenn Close.

21 min

Ana Ortiz, Ashley Darby

Andy Cohen interviews Ashley Darby and Ana Ortiz.

21 min

Robbie Williams, Julia Stiles

Andy Cohen interviews Julia Stiles and Robbie Williams.

21 min

Sai De Silva, Erin Lichy

Andy Cohen interviews Sai De Silva and Erin Lichy.

21 min

Chrishell Stause, Lisa Barlow

Andy Cohen interviews Lisa Barlow and Julia Garner.

21 min

Patricia Arquette, Gwendoline Christie

Andy Cohen interviews Gwendoline Christie and Patricia Arquette.

21 min

Keke Palmer, Dr. Wendy Osefo

Andy Cohen interviews Dr. Wendy Osefo and Keke Palmer.

21 min

Keith Allen, Mekki Leeper

Andy Cohen interviews Keith Allen and Mekki Leeper.

21 min

Bozoma Saint John, Jenna Lyons

Andy Cohen interviews Bozoma Saint John and Jenna Lyons.

21 min

Julia Fox, Bronwyn Newport

Andy Cohen interviews Julia Fox and Bronwyn Newport.

21 min

TJ Dinch, Taylor Ann Green

Andy Cohen interviews Taylor Ann Green and TJ Dinch.

21 min

Quad Webb, Mia Thornton

Host Andy Cohen discusses pop-culture events with guests and viewers.

21 min

Daisy Kelliher, Aesha Scott

Andy Cohen interviews Daisy Kelliher and Aesha Scott.

21 min

Garcelle Beauvais, Bob Harper

Andy Cohen interviews Garcelle Beauvais and Bob Harper.

21 min

Chloe Fineman, Mary Cosby

Andy Cohen interviews Chloe Fineman and Mary Cosby.

21 min

Austen Kroll, Patricia Altschul

Andy Cohen interviews Austen Kroll and Patricia Altschul.

21 min

Gizelle Bryant, Robyn Dixon

Andy Cohen interviews Gizelle Bryant and Robyn Dixon.

21 min

Capt. Jason Chambers, Tzarina Mace-Ralph

Andy Cohen interviews Capt. Jason Chambers and Tzarina Mace-Ralph.

21 min

Kyle Richards, Harry Hamlin

Andy Cohen interviews Kyle Richards and Harry Hamlin.

21 min

Drew Barrymore, Nate Burleson

Andy Cohen interviews Drew Barrymore and Nate Burleson.

21 min

Maddi Reese, Craig Conover

Andy Cohen interviews Maddi Reese and Craig Conover.

21 min

Amy Schumer, Brianne Howey

Andy Cohen interviews Amy Schumer and Brianne Howey.

21 min

The Women of Saturday Night Live

Andy Cohen interviews Cecily Strong, Rachel Dratch, Ana Gasteyer, Cheri Oteri, and Laraine Newman.

21 min

Lindsay Hubbard, Ciara Miller

Andy Cohen interviews Lindsay Hubbard and Ciara Miller.

21 min

Anya Taylor-Joy, Miles Teller

Andy Cohen interviews Anya Taylor-Joy and Miles Teller.

21 min

Dr. Contessa Metcalfe, Lateasha Lunceford

Andy Cohen interviews Dr. Contessa Metcalfe and Lateasha Lunceford.

21 min

Jon Hamm, Morris Chestnut

Andy Cohen interviews Jon Hamm and Morris Chestnut.

21 min

Jennifer Tilly, Crystal Kung Minkoff

Andy Cohen interviews Jennifer Tilly and Crystal Kung Minkoff.

21 min

Dolores Catania, Carl Radke

Andy Cohen interviews Dolores Catania and Carl Radke.

21 min

Michols Peña, Salley Carson

Andy Cohen interviews Michols Peña and Salley Carson

21 min

Stacey Rusch, Dr. Simone Whitmore

Andy Cohen interviews Stacey Rusch and Dr. Simone Whitmore.

21 min

Gabrielle Union, Jay Ellis

Andy Cohen interviews Gabrielle Union and Jay Ellis.

21 min

Denise Richards, Sutton Stracke

Andy Cohen interviews Denise Richards and Sutton Stracke.

21 min

Kyle Cooke, Tom Sandoval

Andy Cohen interviews Kyle Cooke and Tom Sandoval.

21 min

Southern Hospitality Season 3 Reunion

Andy Cohen sits down with the crew from Republic to discuss all of the workplace drama and romance from this season.

54 min

Porsha Williams, Law Roach

Andy Cohen interviews Porsha Williams and Law Roach.

21 min

Adair Werley, Michelle Collins

Andy Cohen interviews Adair Werley and Michelle Collins.

21 min

Dorit Kemsley, Gabby Windey, Dylan Efron

Andy Cohen interviews Dorit Kemsley, Gabby Windey and Dylan Efron.

21 min

Liza Treyger, West Wilson

Andy Cohen interviews Liza Treyger and West Wilson.

21 min

Anitta, Uzo Aduba

Andy Cohen interviews Anitta and Uzo Aduba.

21 min

Shamea Morton, Toya Bush-Harris

Andy Cohen interviews Shamea Morton and Toya Bush-Harris.

21 min

Chrissy Teigen, Harry Van Vliet

Andy Cohen interviews Chrissy Teigen and Harry Van Vliet.

21 min

Leslie Bibb, Garcelle Beauvais

Andy Cohen interviews Garcelle Beauvais and Leslie Bibb.

21 min

Ciara Miller, Amanda Batula

Andy Cohen interviews Ciara Miller and Amanda Batula.

21 min

Annaleigh Ashford, Venita Aspen

Andy Cohen interviews Venita Aspen and Annaleigh Ashford.

21 min

Will Packer, Angela Oakley

Andy Cohen interviews Will Packer and Angela Oakley.

21 min

Erika Jayne, Bozoma Saint John

Andy Cohen interviews Erika Jayne and Bozoma Saint John.

21 min

Imrul Hassan, Jesse Solomon

Andy Cohen interviews Imrul Hassan and Jesse Solomon.

21 min

Craig Conover, Shep Rose, Austen Kroll

Andy Cohen interviews Craig Conover, Shep Rose and Austen Kroll.

21 min

Kelli Ferrell, Michelle Buteau

Andy Cohen interviews Kelli Ferrell and Michelle Buteau.

21 min

Bill Murray, Naomi Watts

Andy Cohen interviews Bill Murray and Naomi Watts.

21 min

Kathryn Hahn, Ike Barinholtz, Chase Sui Wonders

Andy Cohen interviews Kathryn Hahn, Ike Barinholtz and Chase Sui Wonders.

21 min

Carl Radke, Madison Lecroy

Andy Cohen interviews Carl Radke and Madison Lecroy.

21 min

Michelle Williams, John Oliver

Andy Cohen interviews Michelle Williams and John Oliver.

21 min

Cynthia Bailey, Danielle Brooks

Andy Cohen interviews Cynthia Bailey and Danielle Brooks.

21 min

Lara Rigby, Mzi Dempers

Andy Cohen interviews Lara Rigby and Mzi Dempers.

21 min

Elisabeth Moss, Maren Morris

Andy Cohen interviews Elisabeth Moss and Maren Morris.

21 min

Lexi Wood, Danielle Schneider

Andy Cohen interviews Lexi Wood and Danielle Schneider.

21 min

Anthony Anderson, Matthew Rhys

Andy Cohen interviews Anthony Anderson and Matthew Rhys.

21 min

Mark Indelicato, Brit Eady

Andy Cohen interviews Mark Indelicato and Brit Eady.

21 min

Brianna Duffield, Marina Marcondes

Andy Cohen interviews Brianna Duffield and Marina Marcondes.

21 min

Kristen Doute, Nia Sanchez Booko

Andy Cohen interviews Kristen Doute and Nia Sanchez Booko.

21 min

Casey Wilson, Paige Desorbo

Andy Cohen interviews Casey Wilson and Paige Desorbo.

21 min

Kristen Kish, Gail Simmons, Tom Colicchio

Andy Cohen interviews Kristen Kish, Gail Simmons and Tom Colicchio.

21 min

Gizelle Bryant, Porsha Williams

Andy Cohen interviews Gizelle Bryant and Porsha Williams.

21 min

Eva Longoria, Sandra Bernhard

Andy Cohen interviews Eva Longoria and Sandra Bernhard.

21 min

Brittany Cartwright, Luke Broderick

Andy Cohen interviews Brittany Cartwright and Luke Broderick.

21 min

Ciara Miller, Madeline Brewer

Andy Cohen interviews Ciara Miller and Madeline Brewer.

21 min

Lisa Vanderpump

Andy Cohen interviews Lisa Vanderpump.

21 min

Elizabeth Perkins, Luann de Lesseps

Andy Cohen interviews Elizabeth Perkins and Luann de Lesseps.

21 min

Connie Britton, Will Forte

Andy Cohen interviews Connie Britton and Will Forte.

21 min

Zack Wickham, Michelle Saniei

Andy Cohen interviews Zack Wickham and Michelle Saniei.

21 min

Tinx, Lexi Wood

Andy Cohen interviews Tinx and Lexi Wood.

21 min

John Benjamin Hickey, Patricia Clarkson

Andy Cohen interviews John Benjamin Hickey and Patricia Clarkson.

21 min

Ariana Madix, Shamea Morton

Andy Cohen interviews Ariana Madix and Shamea Morton.

21 min

Melissa Rivers, Nate Salmon

Andy Cohen interviews Melissa Rivers and Nate Salmon.

21 min

Jesse Lally, Danny Booko

Andy Cohen interviews Jesse Lally and Danny Booko.

21 min

West Wilson, Jesse Solomon

Andy Cohen interviews West Wilson and Jesse Solomon.

21 min

Snoop Dogg, Lizzo

Andy Cohen interviews Snoop Dogg and Lizzo.

21 min

Ashley Darby, Kelli Ferrell

Andy Cohen interviews Ashley Darby and Kelli Ferrell.

21 min

Harry Van Vliet, Nicolas Cattelan

Andy Cohen interviews Harry Van Vliet and Nicolas Cattelan.

21 min

Janet Caperna, Jason Caperna

Andy Cohen interviews Janet Caperna and Jason Caperna.

21 min

Lindsay Hubbard, Kyle Cooke

Andy Cohen interviews Lindsay Hubbard and Kyle Cooke.

21 min

Elizabeth Banks, Amanda Peet

Andy Cohen interviews Elizabeth Banks and Amanda Peet.

21 min

La La Anthony, Phaedra Parks

Andy Cohen interviews La La Anthony and Phaedra Parks.

21 min

Capt. Kerry Titheradge, Hannah Ferrier

Andy Cohen interviews Capt. Kerry Titheradge and Hannah Ferrier.

21 min

Jasmine Goode, Yvonne Strahovski

Andy Cohen interviews Jasmine Goode and Yvonne Strahovski.

21 min

Amanda Batula, Kristin Cavallari

Andy Cohen interviews Amanda Batula and Kristin Cavallari.

21 min

Hoda Kotb, Mario Cantone

Andy Cohen interviews Hoda Kotb and Mario Cantone.

21 min

Shannon Storms Beador, Drew Sidora

Andy Cohen interviews Shannon Storms Beador and Drew Sidora.

21 min

Scott Porter, Fraser Olender

Andy Cohen interviews Scott Porter and Fraser Olender.

21 min

Bryce Dallas Howard, Michelle Saniei

Andy Cohen interviews Bryce Dallas Howard and Michelle Saniei.

21 min

Cynthia Nixon, Ricki Lake

Andy Cohen interviews Cynthia Nixon and Ricki Lake.

21 min

Luann du Lesseps, Joel Kim Booster

Andy Cohen interviews Luann du Lesseps and Joel Kim Booster.

21 min

Rainbeau de Roos, Anthony Iracane

Andy Cohen interviews Rainbeau de Roos and Anthony Iracane.

21 min

Tom Schwartz, Jax Taylor

Andy Cohen interviews Tom Schwartz and Jax Taylor.

21 min

Alexia Nepola, Marysol Patton

Andy Cohen interviews Alexia Nepola and Marysol Patton.

21 min

Ciara, Anthony Ramos

Andy Cohen interviews Ciara and Anthony Ramos.

21 min

Angela Oakley, Cynthia Bailey

Andy Cohen interviews Angela Oakley and Cynthia Bailey.

21 min

Arnold Schwarzenegger

Andy Cohen interviews Arnold Schwarzenegger.

21 min

Haim

Andy Cohen interviews Haim.

21 min

Kiki Barth, Larsa Pippen

Andy Cohen interviews Kiki Barth and Larsa Pippen.

21 min

Charlize Theron, Henry Golding

Andy Cohen interviews Charlize Theron and Henry Golding.

21 min

Phaedra Parks, Ariana Biermann

Andy Cohen interviews Phaedra Parks and Ariana Biermann.

21 min

Barbara Kulaif, Damo Yorg

Andy Cohen interviews Barbara Kulaif and Damo Yorg.

21 min

Abby Elliott, Jesse Lally

Andy Cohen interviews Abby Elliot and Jesse Lally.

21 min

Stephanie Shojaee, Sara Foster

Andy Cohen interviews Stephanie Shojaee and Sara Foster.

21 min

Tamra Judge, Steven McBee Jr.

Andy Cohen interviews Tamra Judge and Steven McBee Jr.

21 min

Sarah Jessica Parker

Andy Cohen interviews Sarah Jessica Parker.

21 min

Amy Sedaris, Dan Levy

Andy Cohen interviews Amy Sedaris and Dan Levy.

21 min

Riley Burruss, Kandi Burruss

Andy Cohen interviews Kandi Burruss and Riley Burruss.

21 min

Lisa Hochstein, Rebecca Romijn

Andy Cohen interviews Lisa Hochstein and Rebecca Romijn.

21 min

Emily Simpson, Leah Kateb

Andy Cohen interviews Emily Simpson and Leah Kateb.

21 min

Tyson Beckford, Octavia Spencer

Andy Cohen interviews Octavia Spencer and Tyson Beckford.

21 min

Meg Stalter, Tracee Ellis Ross

Andy Cohen interviews Tracee Ellis Ross and Meg Stalter.

21 min

Brittany Cartwright, Zack Wickham

Andy Cohen interviews Brittany Cartwright and Zack Wickham.

21 min

Guerdy Abraira, Tommy Dorfman

Andy Cohen interviews Guerdy Abraira and Tommy Dorfman.

21 min

Shannon Storms Beador, Denise Welch

Andy Cohen interviews Shannon Storms Beador and Denise Welch.

21 min

Kristen Johnson, Leanne Morgan

Andy Cohen interviews Kristen Johnston and Leanne Morgan.

21 min

Jess Theron, Hugo Ortega

Andy Cohen interviews Jess Theron and Hugo Ortega.

21 min

Gia Giudice, Brooks Marks, Emira D'Spain

Andy Cohen interviews Brooks Marks, Gia Giudice and Emira D'Spain.

21 min

Julia Lemigova, Isaac Mizrahi

Andy Cohen interviews Julia Lemigova and Issac Mizrahi.

21 min

Katie Ginella, Kim Zolciak

Andy Cohen interviews Katie Ginella and Kim Zolciak.

21 min

Pamela Anderson, Liam Neeson

Andy Cohen interviews Pamela Anderson and Liam Neeson.

21 min

Bowen Yang, Matt Rogers

Andy Cohen interviews Bowen Yang and Matt Rogers.

21 min

Alison Brie, Dave Franco

Andy Cohen interviews Alison Brie and Dave Franco.

21 min

Adriana De Moura, Loni Love

Andy Cohen interviews Adriana De Moura and Loni Love.

21 min

Gina Kirschenheiter, Julia Garner

Andy Cohen interviews Gina Kirschenheiter and Julia Garner.

21 min

MGK, Pamela Adlon

Andy Cohen interviews MGK and Pamela Adlon.

21 min

Kyle Stillie, Fraser Olender

Andy Cohen interviews Kyle Stillie and Fraser Olender.

21 min

Seth Rogen, Rose Byrne, Luke Macfarlane

Andy Cohen interviews Seth Rogen, Rose Byrne and Luke Macfarlane.

21 min

Amaya Espinal, Bryan Arenales, Olandria Carthen, Nic Vansteenberghe

Andy Cohen interviews Amaya Espinal, Bryan Arenales, Olandria Carthen and Nic Vansteenberghe.

21 min

Heather Dubrow, Kaylor Martin

Andy Cohen interviews Heather Dubrow and Kaylor Martin.

21 min

Sharon Stone, Bob Odenkirk

Andy Cohen interviews Sharon Stone and Bob Odenkirk.

21 min

Anthony Iracane, Barbara Kulaif

Andy Cohen interviews Anthony Iracane and Barbara Kulaif.

21 min

Ashlee Simpson Ross, Dylan O'Brien

Andy Cohen interviews Ashlee Simpson Ross and Dylan O'Brien.

21 min

Michelle Williams, Joy Behar

Andy Cohen interviews Michelle Williams and Joy Behar.

21 min

Jennifer Pedranti, Alexia Nepola

Andy Cohen interviews Jennifer Pedranti and Alexia Nepola.

21 min

Chaka Khan, Patti LaBelle, Stephanie Mills

Andy Cohen interviews Chaka Khan, Patti LaBelle and Stephanie Mills.

21 min

Capt. Kerry Titheradge, Michelle Collins

Andy Cohen interviews Captain Kerry Titheradge and Michelle Collins.

21 min

Angie Katsanevas, Demi Lovato

Andy Cohen interviews Angie Katsanevas and Demi Lovato.

21 min

Mark Ronson, Brooks Nader

Andy Cohen interviews Mark Ronson and Brooks Nader.

21 min

Gretchen Rossi, Larsa Pippen

Andy Cohen interviews Gretchen Rossi and Larsa Pippen.

21 min

Tom Blyth, Russell Tovey

Andy Cohen interviews Tom Blyth and Russell Tovey.

21 min

Kyle MacLachlan, Sherri Shepherd

Andy Cohen interviews Sherri Sheperd and Kyle MacLachlan.

21 min

Madelaine Petsch, Bronwyn Newport

Andy Cohen interviews Bronwyn Newport and Madelaine Petsch.

21 min

Teyana Taylor, Ego Nwodim

Andy Cohen interviews Ego Nwodim and Teyana Taylor.

21 min

Adriana de Moura, Tamra Judge

Andy Cohen interviews Tamara Judge and Adriana De Moura.

21 min

Jesse Williams, Regina Hall

Andy Cohen interviews Jesse Williams and Regina Hall.

21 min

Aesha Scott, Victoria Sanjuan

Andy Cohen interviews Aesha Scott and Victoria Sanjuan.

21 min

Lisa Barlow and Sean Avery

Andy Cohen interviews Lisa Barlow and Sean Avery.

21 min

Mariah Carey

Andy Cohen interviews Mariah Carey.

21 min

Jimmy Fallon, Bozoma Saint John

Andy Cohen interviews Jimmy Fallon and Bozoma Saint John.

21 min

Latto, Gizelle Bryant

Andy Cohen interviews Latto and Gizelle Bryant.

21 min

Captain Sandy Yawn, Nathan Gallagher

Andy Cohen interviews Captain Sandy Yawn and Nathan Gallagher.

21 min

Adam Pally, Mary Cosby

Andy Cohen interviews Adam Pally and Mary Cosby.

21 min

Julia Roberts

Andy Cohen interviews Julia Roberts.

21 min

Bridget Everett, Heather Dubrow

Andy Cohen interviews Bridget Everett and Heather Dubrow.

21 min

Jeff Lewis, Ashley Darby

Andy Cohen interviews Jeff Lewis and Ashley Darby.

21 min

Jennifer Hudson, Laverne Cox

Andy Cohen interviews Jennifer Hudson and Laverne Cox.

21 min

Lukas Gage, Whitney Rose

Andy Cohen interviews Lukas Gage and Whitney Rose.

21 min

Jennifer Lopez

Andy Cohen interviews Jennifer Lopez.

21 min

Bette Midler

Andy Cohen interviews Bette Midler.

21 min

Keiarna Stewart, Phoebe Robinson

Andy Cohen interivews Keiarna Stewart and Phoebe Robinson.

21 min

Kizzi Kitchener, Josh Bingham

Andy Cohen interviews Kizzi Kitchener and Josh Bingham.

21 min

Meredith Marks, Allison Williams

Andy Cohen interviews Meredith Marks and Allison Williams.

21 min

Allison Janney, Keri Russell

Andy Cohen interviews Allison Janney and Keri Russell.

21 min

Shannon Storms Beador, Garcelle Beauvais

Andy Cohen interviews Shannon Storms Beador and Garcelle Beauvais.

21 min

Lauren Smith, Mariah Smith, Rachel Smith, Stacey Rusch

Andy Cohen interviews Lauren Smith, Mariah Smith, Rachel Smith and Stacey Rusch.

21 min

Captain Sandy Yawn, Joe Bradley

Andy Cohen interviews Captain Sandy Yawn and Joe Bradley.

21 min

Erin Lichy, Lisa Barlow

Andy Cohen interviews Erin Lichy and Lisa Barlow.

21 min

Tessa Thompson, Justine Lupe

Andy Cohen interviews Tessa Thompson and Justine Lupe.

21 min

Chrishell Stause, Gina Kirschenheiter

Andy Cohen interviews Chrishell Stause and Gina Kirschenheiter.

21 min

Karamo and Tia Glover

21 min

Isla Fisher and Judd Apatow

21 min

Sarah Paulson and Bronwyn Newport

21 min

Janelle James and Jerrod Carmichael

21 min

Brittany Snow and Dakota Fanning

21 min

Danielle Schneider and Angel Massie

21 min

Captain Jason Chambers and Daisy Kelliher

21 min

Heather Gay and Ricki Lake

21 min

Tiffany Haddish and Gayle King

21 min

Patti Lupone and Anderson Cooper

21 min

Max Salvador and Victoria Sanjuan

21 min

Britani Bateman, Marcus Johnson and Natalie Maguire

21 min

Madison LeCroy and Austen Kroll

21 min

Rep. Robert Garcia and Kyle Richards

21 min

Monique Samuels and Sarah Sherman

21 min

Mickey Guyton and Joe Bradley

21 min

Heather Gay and Matt Rogers

21 min

Shep Rose and Molly O'Connell

21 min

Dorit Kemsley and Zooey Deschanel

21 min

Dr. Simone Whitmore and Keiarna Stewart

21 min

Victoria Beckham and Kerry Washington

21 min

Meredith Marks and Noah Schnapp

21 min

S.E. Cupp and Craig Conover

21 min

Erika Jayne and Brooks Nader

21 min

Ashley Darby & Toya Bush-Harris

21 min

Kate Hudson and Ice Spice

21 min