Chelsea Lately Season 4, Episode 11: Kaley Cuoco

Robin Thicke

We're starting off the new year with Robin Thicke and his Sex Therapy...like father like son. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Guy Branum are on the panel.

30 min

Mary J. Blige

We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

30 min

Holly Madison

We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

30 min

Joel David Moore

Holly Madison is dropping on by her old E! family today...we've missed her, too. Comedian Donnel Rawlings, comedian Heather McDonald and comedian Gary Valentine.

30 min

Giuliana & Bill Rancic

Word on the street is Giuliana and Bill Rancic are trying to have a baby. What're the odds that we'll get any sort of big announcement? Comedian Brad Wollack, comedian Natasha Leggero and comedian Matt Braunger.

30 min

Aisha Tyler

We welcome back the very funny Aisha Tyler, from the new show Archer. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.

30 min

Amy Brenneman

Amy Brenneman of Private Practice stops by, perhaps with some doctorly advice. Comedian John Caparulo, comedian Jen Kirkman and comedian Dan Levy.

30 min

Snooki, Pauly D and The Situation

Fist pumps all around for Jersey Shore's Snooki, Pauly D and The Situation. Comedian Chris Franjola, comedian Whitney Cummings and TV personality Ross Mathews.

30 min

David Arquette

David Arquette is back and telling us all about his new play The Female of the Species and the Golden Globes! Comedians Michelle Collins and Randy and Jason Sklar

30 min

Adrianne Palicki

Clear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's Tyra). Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Eric Price.

30 min

James Van Der Beek

James Van Der Beek is in the new movie Formosa Betrayed and popping up all over TV—even here! E!'s own Michael Yo, comedian Sarah Colonna and comedian Guy Branum.

30 min

Katharine McPhee

30 min

Jill Scott

30 min

Dax Shepard

30 min

Staff Book Club

30 min

Camila Alves

30 min

Andy Whitfield

30 min

Shorty Rossi

30 min

Julie Benz

30 min

Ozzy Osbourne

30 min

Amanda Seyfried

30 min

Dave Salmoni

We're beyond pleased to welcome back our animal guy Dave Salmoni and his new animal friends. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Mo Mandel.

30 min

Channing Tatum

30 min

Kate Flannery

We get down to business with The Office's Kate Flannery. Comedian Loni Love, comedian Dan Levy and comedian Whitney Cummings.

30 min

Jackie Collins

Things get really scandalous when author Jackie Collins stops by with her new book, Poor Little Bitch Girl. Comedian Chris Hardwick, comedian Jen Kirkman and comedian Jo Koy.

30 min

Lisa Edelstein

Lisa Edelstein from House is back again...Wait, so who's running Princeton Plainsboro? Comedian Josh Wolf, comedian Heather McDonald and comedian Ryan Stout.

30 min

Eli Roth

30 min

Keshia Knight Pulliam

House of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable would be so proud. Comedian Loni Love, TV personality Rove McManus and comedian Michelle Collins

30 min

Danica Patrick

We're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea Lately today. Comedian Josh Wolf, comedian Whitney Cummings and comedian Jo Koy.

30 min

Radha Mitchell

Things might get wild with Radha Mitchell star of the new thrilling horror movie The Crazies. Comedian John Caparulo, comedian Bill Bellamy and actress-comedian Arden Myrin.

30 min

Parker Posey

The Chelsea Lately cast do a Kardashian skit. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

30 min

Sean William Scott

From the new movie Cop Out we've got Seann William Scott in our custody today. Comedian Chris Hardwick and Comedians Randy and Jason Sklar.

30 min

Kendra & Hank Baskett

Kendra and Hank Baskett are here to tell us all about the spellbinding new season of Kendra. E!'s own Michael Yo, comedian Sarah Colonna and comedian Jo Koy.

30 min

Single Staffers, Handler Edition

Please enjoy a very special Handler Edition of Single Staffers. Comedian Matt Bruanger, comedian Heather McDonald and comedian Moshe Kasher.

30 min

Gabourey Sidibe

From Precious, the Academy Award-nominated Gabourey Sidibe is here. TV personality Ross Mathews, comedian Christina Pazsitzky and comedian Guy Branum.

30 min

Kevin McKidd

Someone got some time away from the O.R., Grey's Anatomy's Kevin McKidd is here. Comedian John Caparulo, comedian Arden Myrin and comedian Chris Franjola.

30 min

Chelsea Chelsea Bang Bang

Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

30 min

Amy Ryan

Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

30 min

Pretty Wild Cast

Alexis Neiers, Gabrielle Neiers and Tess Taylor are here from their aptly titled new series on E! Pretty Wild. Comedian Brad Wollack, comedian Dan Levy and comedian Josh Wolf.

30 min

Shenae Grimes

90210's Shenae Grimes is here to give us the deets on all things West Beverly. Comedian Bobby Lee, comedian T.J. Miller and comedian Whitney Cummings.

30 min

Rachael Harris

From the highly anticipated Diary of a Wimpy Kid, the purely entertaining Rachael Harris is here. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.

30 min

Avril Lavigne

We catch up with Avril Lavigne, who sings "Alice," the title song from Tim Burton's Alice in Wonderland. Comedian Sarah Colonna, comedian/TV host Rove McManus and comedian Mo Mandel.

30 min

Duane "Dog" Chapman

We're so thrilled to welcome the author of Where Mercy Is Shown, Mercy Is Given, Dog the Bounty Hunter. Comedian John Caparulo, comedian Heather McDonald and TV personality Ross Mathews.

30 min

Kelly Cutrone

30 min

Scott Wolf

30 min

Crispin Glover

30 min

Blake Shelton

30 min

Ludacris

Ludacris is back with his new album Battle of the Sexes and this time he's bringing drinks. Comedian Ben Gleib, comedian Natasha Leggero and comedian Guy Branum.

30 min

Johnny Weir

Johnny Weir is here, and unfortunately our show is not "on ice" this week. Comedian Jo Koy, comedian Lil JJ and comedian Sarah Colonna.

30 min

Erykah Badu

30 min

Justin Bieber

Chuy Bravo wrote a book, Little Nuggets of Wisdom, and he's here to share them. This, BTW, is all 100 percent for real, for real, girl. Comedian Heather McDonald, comedians Randy & Jason Sklar.

30 min

Jennifer Love Hewitt

Author of The Day I Shot Cupid, Jennifer Love Hewitt is here. Comedian Brad Wollack, E!'s own Michael Yo and Comedian Mo Mandel,

30 min

Ed Asner

Find out how spunky Chelsea can really be when TV Icon and star of Up Ed Asner stops by. Comedian Josh Wolf, comedian Loni Love and comedian Wil Anderson.

30 min

Blake MyCoskie

Things get real philanthropic up in here with Tom's Shoes founder Blake Mycoskie. Comedian Greg Behrendt, comedian Jen Kirkman and comedian Matt Braunger.

30 min

Taraji P. Henson

From the highly anticipated movie Date Night, the Academy Award-nominated Taraji P. Henson is here. Comedian Chris Franjola, comedian Chris Hardwick, TV personality Ross Mathews.

30 min

Tiny & Toya

From BET's Tiny & Toya, BFFs Tiny & Toya are here. Comedian Whitney Cummings, actress Cloris Leachman and TV personality Ross Mathews.

30 min

Our 500th Episode

Come celebrate a real milestone at Chelsea Lately—tonight's our 500th episode! Comedian Jo Koy, comedian Sarah Colonna and comedian Josh Wolf.

30 min

Dave Salmoni

Resident animal expert Dave Salmoni is back with some hopefully furry friends. Comedian Dan Levy, comedian Arden Myrin and comedian Lavell Crawford.

30 min

Erin Andrews & Maksim Chmerkovskiy

Dancing With the Stars' hottest couple Erin Andrews and Maksim Chmerkovskiy. Comedian John Caparulo, comedian Heather McDonald and comedian Donnell Rawlings.

30 min

Gretchen Wilson

30 min

Amy & Matt Roloff

30 min

Katie Cassidy

30 min

Ted Allen

30 min

Michael Weatherly

30 min

Jerry Weintraub

30 min

Jeffrey Dean Morgan

30 min

Brooke Shields

30 min

Molly Ringwald

30 min

Busy Philipps

30 min

Monica

30 min

Michael Lewis

30 min

Amanda Seyfried

30 min

Laura Bell Bundy

30 min

Asian Singles with Jo Koy

30 min

Carson Kressley

30 min

Bradley Whitford

30 min

Marisa Miller

30 min

Mary Lynn Rajskub

30 min

Damon Wayans

30 min

James Van Praagh

30 min

Judge Lately

30 min

Tim Roth

30 min

Zach Gilford

30 min

Snoop Dogg and Mike Epps

30 min

Justin Halpern

The man behind all things Shit My Dad Says, Justin Halpern is here. Comedian Bobby Lee, comedian Jen Kirkman and comedian Dov Davidoff.

30 min

Colin Hanks

Tonight we welcome Colin Hanks, one of The Good Guys from the new Fox drama. Comedian Heather McDonald, comedian Randy Sklar and musician Jeff Wild.

30 min

Clay Aiken

Clay Aiken is here, seriously, with his new CD Tried and True. Comedian Ben Gleib, comedian Loni Love and Comedian Gary Valentine.

30 min

Holly Madison

Holly Madison is back with her new show Holly's World. Comedian Chris Hardwick, comedian Guy Branum and actress-comedian Arden Myrin.

30 min

Stephen Moyer

True Blood is returning and Stephen Moyer is here, so get excited...or scared?! I'm not really sure. Comedian Jo Koy, comedian Eric Price and comedian Chris Franjola.

30 min

Denis Leary

Star of all things Rescue Me the hilarious Denis Leary is here. Comedian Steve Marmalstein, comedian Natasha Leggero and TV personality Ross Mathews.

30 min

Sarah McLachlan

We're getting a little Lilith tonight when Sarah McLachlan stops by and talks her new album, Laws of Illusion. Comedian Jo Koy, E!'s own Michael Yo and comedian Sarah Colonna.

30 min

Lil Jon

We're getting crunk with Lil Jon and his new album Crunk Rock…YEAAAAHHHH! Comedian John Caparulo, comedian Christina Pazsitzky and comedian Josh Wolf.

30 min

Roy Handler & Charley

Learn how to make cupcakes with Roy and Charley tonight. Comedian Brad Wollack, comedian Dan Levy and comedian Bobby Lee.

30 min

A.J. Khubani

Learn about the borderline amazing new As Seen on TV Products with A.J. Khubani. Comedian Chris Franjola, comedian Whitney Cummings and comedian Finesse Mitchell.

30 min

Mary McCormack

Star of In Plain Sight Mary McCormack graces us with her presence. Comedian Joe DeRosa, comedian Heather McDonald and comedian Josh Wolf.

30 min

Ron Artest

Comedian Matt Braunger, comedian Moshe Kasher and comedian Guy Branum. Lakers champ Ron Artest tries to get into Chelsea's pants and chats about his NBA win. Plus, hear about his budding music career!

30 min

Ashley Greene

Actress Ashley Greene on her new movie, "The Twilight Saga: Eclipse"; Round table discussion with comics Mo Mandel, Arden Myrin, and Ross Mathews.

30 min

T.I.

Rapper T.I. on his new album, "King Uncaged"; Round table discussion with comics Sarah Colonna, Jamie Kaler, and Josh Wolf.

30 min

Bryce Dallas Howard

From the most-anticipated movie in the country, Eclipse, Bryce Dallas Howard is here. Comedian Brad Wollack, comedian John Caparulo and comedian Christina Pazsitzky

30 min

Joe's Crab Shack

Check out Chuy as the new spokesperson for Joe's Crab Shack...You're welcome crabs. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib

30 min

Sam Trammell

True Blood's favorite shapeshifter Sam Trammell is back. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib

30 min

Claire Smith

Learn about the summer's best drinks with Belvedere's Claire Smith. Comedian Jason Sklar, comedian Natasha Leggero and comedian Gary Valentine

30 min

Pharrell

Pharrell does a lot, like producing the soundtrack and composing the score for Despicable Me. Comedian Jo Koy, comedian Whitney Cummings and TV personality Ross Mathews.

30 min

Kristin Cavallari

Kristin Cavallari is here and has all the info you're dying to know about the final season of The Hills. Comedian Chris Hardwick, comedian Heather McDonald and comedian Dov Davidoff

30 min

Dave Salmoni

Canadian animal trainer Dave Salmoni on his new show, "Savaged with Dave Salmoni"; Round table discussion with comics Jason Sklar, Natasha Leggero, and Gary Valentine.

30 min

Susan Sarandon

Actress Susan Sarandon on her upcoming reality ping-pong series; Round table discussion with comics Jo Koy, Ben Gleib, and Brad Wollack.

30 min

Anna Paquin

Sink your teeth into this: tonight we welcome Anna Paquin from HBO's True Blood. Rapper Lil John, rapper Big Boi and rapper Rick Ross.

30 min

Arsenio Hall

Dust off your fists, girls, because Arsenio Hall is in the house. Comedian Chris Franjola, comedian Christina Pazsitzky and TV personality Ross Mathews

30 min

Frank Grillo

Actor Frank Grillo on his show, "The Gates"; Round table discussion with comics Loni Love, Josh Wolf, and Greg Proops.

30 min

Kathy Griffin

Comedian Kathy Griffin on her show, "Kathy Griffin: My Life on the D-List"; Round table discussion with comics Jo Koy, Michael Yo, and Whitney Cummings.

30 min

Chicken Charlie

Fry cook Chicken Charlie discusses frying food; Round table discussion with comics Chris Hardwick, Heather McDonald, and Rove McManus.

30 min

Ron Livingston

Actor Ron Livingston on his new film, "Dinner with Schmucks"; Round table discussion with comics Ross Mathews, Sarah Colonna, Guy Branum.

30 min

Gabrielle Reece

Tonight's guest is volleyball pro Gabby Reece. At the Round Table: John Caparulo, Christina Pazsitzky, Matt Braunger.

30 min

Lisa Lampanelli

Tonight's guest is actress Lisa Lampanelli. At the Round Table: Brad Wollack, Jo Koy, James Van Praagh.

30 min

Fat Joe

Fat Joe returns with his new album, The Darkside. Comedian Chris Franjola, actress-comedian Arden Myrin and TV personality Ross Mathews

30 min

Eva Mendes

From The Other Guys, Eva Mendes is here. Comedian Dan Levy, comedian Natasha Leggero and comedian Ben Gleib.

30 min

Bethenny Frankel

Star of Bravo's Bethenny Getting Married?, Bethenny Frankel is here. Comedian Josh Wolf, comedian Whitney Cummings and comedian Guy Branum

30 min

Margaret Cho

Margaret Cho tells us about her new comedy/music album Cho Dependent. Comedian Heather McDonald, comedian Hyla Mathews and TV personality Ross Mathews.

30 min

Alanis Morissette

We're checking in with Alanis Morissette who's working her acting chops on the new season of Weeds. Comedian Bobby Lee, comedian Loni Love and comedian Dov Davidoff.

30 min

Extra Round Table

Extra Round Table. Comedian Jo Koy, comedian Sarah Colonna and comedian Jason Sklar

30 min

Kim Raver

Grey's Anatomy star Kim Raver tells us about her foray into the Lifetime TV movie, Bond of Silence. Comedian Finesse Mitchell, actress-comedian Arden Myrin, and TV personality Ross Mathews

30 min

Kim & Kourtney Kardashian

Kim and Kourtney Kardashian are here to make sure everyone is still Keeping Up With the Kardashians. Comedian Bill Bellamy, comedian Natasha Leggero and comedian Josh Wolf.

30 min

Jennifer Aniston

Jennifer Aniston is here telling us about her new film The Switch. Comedian John Caparulo, comedian Whitney Cummings and comedian Brad Wollack.

30 min

Elisabeth Shue

From the most frightening 3D movie of the summer, Piranha: 3D, Elisabeth Shue is here. Comedian Chris Franjola, comedian Owen Benjamin and comedian Jo Koy

30 min

Eli Roth

Eli Roth tells us about his latest film The Last Exorcism. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Gary Valentine.

30 min

Rufus Wainwright

Rufus Wainwright tells us about his tour and latest CD, All Days are Nights: Songs for Lulu. Comedian Josh Wolf, comedian Heather McDonald and musician Jeff Wild.

30 min

Jerry Springer

Jerry Springer tells us about his foray into game shows as host of GSN's Baggage. Comedian Randy Sklar, comedian Christina Pazsitzky and comedian Guy Branum.

30 min

Angie Harmon

Angie Harmon tells us about her hugely popular show Rizzoli & Isles. Comedian Ben Gleib, comedian Godfrey and comedian Jo Koy

30 min

Jewel

Jewel returns and tells us about her new album, Sweet and Wild. Comedian Brad Wollack, comedian Natasha Leggero and comedian Steve Marmalstein.

30 min

Louise Roe

Host of CW's Plain Jane Louise Roe is here to make over the staff of Chelsea Lately. Comedian Josh Wolf, comedian John Caparulo and musician Jo Koy.

30 min

Extra Roundtable

You asked for more round table, tonight you're getting more round table. You're welcome, America. Comedian Chris Franjola, comedian Loni Love and comedian Joe DeRosa

30 min

Mel B

Mel B. tells us about her new Style Network show Mel B: It's a Scary Life. Comedian Greg Proops, actress-comedian Arden Myrin and comedian-host Rove McManus.

30 min

Ne-Yo

R&B singer Ne-Yo on his new album, "Libra Scale "; Round table discussion with comics Michael Yo, Jen Kirkman, and Ross Mathews.

30 min

B.o.B.

VMA performer and five-time nominee B.o.B is here with his No. 1 album B.o.B Presents: The Adventures of Bobby Ray. Comedian Matt Braunger, comedian Heather McDonald and comedian Josh Wolf.

30 min

Extra Roundtable

An extra-long Round Table. You're welcome, America. Comedian T. J. Miller, comedian Sarah Colonna and comedian Dov Davidoff.

30 min

Extra Roundtable

An extra-long Round Table. You're welcome, America. Comedian Ben Gleib, actress-comedian Whitney Cummings and comedian Jo Koy.

30 min

Emma Stone

From Easy A, the can-do-no-wrong-in-my-book Emma Stone is here. Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Kevin Hart.

30 min

Snooki and Pauly D

Get ready to GTL because Jersey Shore's Snooki and Pauly D are back. Comedian Donnell Rawlings, comedian Natasha Leggero and comedian Brad Wollack.

30 min

Usher

Usher has a new album, Versus, is on tour and is hanging out with us tonight, everyone rejoice. Comedian Loni Love, comedian Chris Franjola and musician Jeff Wild.

30 min

Jared Leto

Jared Leto, lead singer of the band '30 Seconds to Mars.' Comedian John Caparulo, comedian Guy Branum and comedian Lavell Crawford

30 min

Meghan McCain

We welcome author of Dirty Sexy Politics, Meghan McCain. Comedian Josh Wolf, comedian Heather McDonald and comedian Gary Valentine.

30 min

Emily Rose

Emily Rose from SyFy's Haven is here. Comedian Matt Braunger, comedian Sarah Colonna and comedian Mo Mandel.

30 min

Laird Hamilton

We're pretty stoked that world-renowned surfer Laird Hamilton returns tonight. Comedian Jason Sklar, comedian Michelle Collins and comedian Jo Koy.

30 min

Kristen Bell

From the hilarious movie You Again, Jersey Shore's No. 1 fan Kristen Bell is here. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews.

30 min

Adam Levine

Adam Levine of Maroon 5 is here with their new album Hands All Over. Comedian Brad Wollack, comedian John Caparulo and writer Diablo Cody.

30 min

Taye Diggs

Star of Private Practice Taye Diggs is here…he may or may not be wearing a shirt. Comedian Jo Koy, comedian Dov Davidoff and comedian Natasha Leggero.

30 min

Dax Shepard

Parenthood's Dax Shepard is here to discuss many a things, one being his new film The Freebie. Comedian Chris Franjola, comedian Dan Levy and TV personality Ross Mathews.

30 min

AnnaLynne McCord

AnnaLynne McCord is here to give us the 411 on all things 90210. Comedian Chris Hardwick, comedian Ben Gleib and actress-comedian Arden Myrin.

30 min

Duane "Dog" Chapman, Beth Smith Chapman,

Dog the Bounty Hunter's Beth and Duane "Dog" Chapman grace our stage tonight. Comedian Moshe Kasher, comedian Heather McDonald and comedian Josh Wolf.

30 min

Tommy Lee

Tommy Lee is here with his latest Methods of Mayhem project A Public Disservice Announcement. TV personality Ross Mathews, comedian Whitney Cummings and comedian Guy Branum.

30 min

Kelly Osbourne

Cohost of E!'s Fashion Police, Kelly Osbourne, is here. Comedian Jo Koy, comedian Randy Sklar and comedian Loni Love.

30 min

Trace Adkins

The cowboy himself, Trace Adkins, is back with his new album Cowboy's Back in Town. Comedian Brad Wollack, comedian Chris Hardwick and comedian Natasha Leggero.

30 min

Leah Remini

Cohost of the new CBS talk show The Talk, Leah Remini is here. Comedian Jo Koy, comedian Sarah Colonna and comedian Greg Proops.

30 min

Lauren Conrad

Author of Sugar and Spice and Lauren Conrad Style the very busy Lauren Conrad is here. Comedian John Caparulo, comedian Josh Wolf and comedian Jim Breuer.

30 min

Amy Brenneman

From Private Practice, the delightful Amy Brenneman returns to the show tonight. Comedian Chris Franjola, actress-comedian Arden Myrin and comedian Kevin Hart.

30 min

Johnny Knoxville

The biggest jackass of them all, Johnny Knoxville from Jackass 3D is here. Comedian Ben Gleib, comedian Loni Love and TV personality Ross Mathews.

30 min

Blake Shelton

The newest member of the Grand Ole Opry, Blake Shelton is here with his new album All About Tonight. Comedian Jo Koy, comedian Heather McDonald and E!'s own Michael Yo.

30 min

Lloyd Banks

Rapper Lloyd Banks. Comedian John Caparulo, comedian Whitney Cummings and comedian Donnell Rawlings.

30 min

Jenny McCarthy

Jenny McCarthy is back with her latest book Love, Lust, and Faking It. Comedian Josh Wolf, musician Jeff Wild and comedian Guy Branum.

30 min

Julian McMahon

From the film Red Julian McMahon graces us with his presence tonight. Comedian Jo Koy, actress-comedian Arden Myrin, and TV personality Ross Mathews.

30 min

Milla Jovovich

Milla Jovovich returns to tell us about her new film Stone. Comedian Josh Wolf, comedian Chris Franjola and comedian Gary Valentine.

30 min

Jennifer Nettles

Jennifer Nettles of Sugarland returns tonight with their new album The Incredible Machine. Comedian John Caparulo, comedian Sarah Colonna and comedian Chris Hardwick.

30 min

Nick Swardson

From Nick Swardson's Pretend Time comedian Nick Swardson is here. Comedian Brad Wollack, comedian Michelle Collins and comedian Bobby Lee.

30 min

Eddie Izzard

Eddie Izzard from Showtime's United States of Tara is here. Comedian Jo Koy, comedian Natasha Leggero and comedian Ryan Stout.

30 min

Benji & Joel Madden

Benji and Joel Madden are here to tell us all about Good Charlotte's new album Cardiology. Comedian Josh Wolf, comedian Heather McDonald and comedian Bill Bellamy.

30 min

Emily Procter

Probably the most pregnant cast member of CSI: Miami, Emily Procter is here. Comedian Dan Levy, comedian Chris Franjola and comedian Sarah Colonna.

30 min

Connie Britton

From dare I say the greatest television show of all time (Friday Night Lights), we welcome Tami Taylor herself, the Emmy-nominated Connie Britton. Writer Diablo Cody, comedian Guy Branum and TV personality Ross Mathews.

30 min

Keenan Cahill

We've got YouTube sensation Keenan Cahill debuting his brand new video on the show tonight. Comedian Josh Wolf, comedian Chris Franjola and comedian Sarah Colonna

30 min

Kendra Wilkinson-Baskett

Kendra Wilkinson-Baskett is here to tell us all about the new season of her show Kendra. Comedian Jo Koy, comedian Matt Braunger and comedian Chris Hardwick

30 min

Starsky & Cox

Find out how all of the stars align tonight with cosmic astrologists Starsky and Cox. Comedian Loni Love, comedian John Caparulo and TV personality Ross Mathews

30 min

Florence Welch

Florence Welch, from one of this year's hottest acts, Florence + the Machine, is here. Comedian Jim Norton, comedian Brad Wollack and actress-comedian Arden Myrin

30 min

Monica Potter

From one of the best shows on TV, Parenthood, Monica Potter is here. Comedian Josh Wolf, comedian Natasha Leggero and comedian Greg Proops

30 min

Trey Songz

Trey Songz is bringing his Passion Pain and Pleasure (also the name of his new CD) to the show tonight, word. Comedian Jo Koy, comedian Heather McDonald and comedian T.J. Miller

30 min

Tom Bergeron

Dancing With the Stars' extraordinary host and Deb's BFF (sorry, Gary) Tom Bergeron is here. Comedian Dan Levy, comedian Sarah Colonna and comedian Gary Valentine

30 min

Nelly

Nelly is dropping by with his new album 5.0. This is for real, this is not just a dream...nailed it. Comedian Chris Franjola, E! News correspondent Michael Yo and TV personality Ross Mathews

30 min

Single security guards

It's the return of Single Staffers...just in time for the holiday season, you're welcome America! Comedian John Caparulo, actress-Comedian Arden Myrin and comedian Ryan Stout.

30 min

Dane Cook

Dane Cook is here with his greatest hits album, I Did My Best. Comedian Jo Koy, comedian Kevin Hart and comedian Ben Gleib

30 min

Taylor Swift

Taylor Swift has a new album, called Speak Now, and she's here to tell us all about it. Topless comedian Brad Wollack, comedian Loni Love and comedian Gary Valentine

30 min

Donald Schultz

Animal expert Donald Schultz is here with an alligator, a prairie dog and a rattlesnake. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews

30 min

John Stamos

One of the greatest gifts television has ever given us, John Stamos who's been guesting on Glee is here. Comedian Josh Wolf, comedian Heather McDonald and TV personality Ross Mathews

30 min

Flo Rida

Flo Rida is here with his new album Only 1 Flo and hopefully some explanation for the state of Florida. Comedian Jo Koy, comedian Sarah Colonna and comedian Mo Mandel

30 min

Cee-Lo Green

Tonight we welcome The Lady Killer himself Cee-Lo Green. Topless Comedian Chris Hardwick, comedian Natasha Leggero and comedian Chris Franjola

30 min

Kate Bosworth

From the new film The Warrior's Way Kate Bosworth is here. Comedian John Caparulo, comedian Matt Braunger and writer Diablo Cody

30 min

Tom Arnold

30 min

Lucy Liu

30 min

Keri Hilson

30 min

Kathy Griffi

30 min

Nicki Minaj

30 min

Cat Cora

30 min

Ciara

30 min

Amy Adams

30 min

Diddy-Dirty Money

30 min

Reese Witherspoon

30 min

Crystal Bowersox

30 min

Natasha Bedingfield

30 min

Keyshia Cole

30 min