Chelsea Lately Season 8, Episode 112: Natasha Lyonne & Uzo Aduba

Bradley Trevor Greive

Australian author Bradley Trevor Greive is on the guest list.

30 min

Adam Scott

Adam Scott is interviewed.

30 min

Kristen Bell

Kristen Bell talks up Season 3 of "House of Lies."

30 min

Idris Elba

Idris Elba is on the guest list, along with panelists Nick Swardson, Sarah Colonna and Michael Rosenbaum.

30 min

Amy Adams

Amy Adams is interviewed. On the panel: Moshe Kasher; Fortune Feimster; Dov Davidoff.

30 min

Zosia Mamet

An interview with Zosia Mamet. Also: Heather McDonald, Julian McCullough and Gary Valentine are on the panel.

30 min

Taylor Schilling

Taylor Schilling is interviewed. On the panel: Giulia Rozzi; Josh Wolf; Loni Love.

30 min

John Leguizamo

John Leguizamo promotes his movie "Ride Along." On the panel: Leah Remini; Mary McCormack; Whitney Cummings.

30 min

Kendall & Kylie Jenner

Kendall and Kylie Jenner promote the Season 9 premiere of "Keeping Up With the Kardashians."

30 min

Heather Graham

Heather Graham is interviewed. On the panel: John Caparulo, Claire Titelman and Ross Mathews.

30 min

Emmy Rossum

Emmy Rossum talks about Season 3 of "Shameless." Ben Gleib is on the panel, along with April Richardson and Ryan Stout.

30 min

David Spade

David Spade ("The Spoils of Babylon") is on the guest list.

30 min

Gabourey Sidibe

Gabourey Sidibe talks about her role on "American Horror Story: Coven." On the panel: Kerri Kenney-Silver; Natasha Leggero; Bobby Lee.

30 min

Timothy Olyphant

Timothy Olyphant chats about Season 5 of "Justified." On the panel: Michael Yo; Jamie Lee; Ross Mathews.

30 min

Andy Samberg

Andy Samberg is interviewed. On the panel: Moshe Kasher; Loni Love; and Gary Valentine.

30 min

Gabrielle Union

Gabrielle Union is interviewed. On the panel: Ron G; Heather McDonald; Ian Karmel.

30 min

Emma Roberts

Emma Roberts is interviewed. On the panel: Chris Franjola; Sarah Colonna; Dustin Ybarra.

30 min

Vanessa Hudgens

Vanessa Hudgens is interviewed. On the panel: John Caparulo; Fortune Feimster; Julian McCullough.

30 min

Michelle Monaghan

Michelle Monaghan ("True Detective") is on the guest list. Panelists: Natasha Leggero; Sarah Tiana; Whitney Cummings.

30 min

Mariska Hargitay

Mariska Hargitay is interviewed. On the panel: Jo Koy; Janine Brito; Ross Mathews.

30 min

Emma Kenney

Emma Kenney ("Shameless") is on the guest list. Panelists: Brody Stevens; Jen Kirkman; Kurt Braunohler.

30 min

McG

Director McG ("3 Days to Kill"). Also: Jeff Wild, Cameron Esposito and Matt Braunger are on the panel.

30 min

Sharon Osbourne

Sharon Osbourne.

30 min

Fashion Week

Chelsea celebrates Fashion Week. On the panel: Eliza Skinner; Lovi Love; Ryan Stout.

30 min

Alison Brie

Alison Brie is interviewed. On the panel: Kerri Kenney-Silver; Liza Treyger; Josh Wolf.

30 min

Demi Lovato

Demi Lovato is interviewed.

30 min

Ross Mathews Hosts, Jackie Collins

Guest host Ross Mathews

30 min

Alex Pettyfer

Alex Pettyfer is on the guest list.

30 min

Scott Speedman

Scott Speedman talks about his role in the comedy "Barefoot."

30 min

Kurt Russell

Kurt Russell chats about starring in "The Art of the Steal." On the panel: Sarah Colonna, Moshe Kasher and Fortune Feimster.

30 min

Julianne Moore

Julianne Moore appears in support of her film "Non-Stop." On the panel: Jen Kirkman, Beth Stelling and Jo Koy.

30 min

Sarah Paulson

Sarah Paulson is interviewed. On the panel: John Caparulo, Morgan Murphy and April Richardson.

30 min

Tara Lipinski & Johnny Weir

Figure skaters Tara Lipinski and Johnny Weir are interviewed. Also: Dov Davidoff, Whitney Cummings and Tone Bell are on the panel.

30 min

Michelle Dockery

Michelle Dockery of "Downton Abbey" is interviewed. On the panel: Kurt Braunohler, Fortune Feimster and Dustin Ybarra.

30 min

Cameron Diaz

Cameron Diaz chats about writing "The Body Book."

30 min

Gabourey Sidibe Hosts, Kid Cudi

Guest host Gabourey Sidibe

30 min

Khloé Kardashian Hosts, Justin Willman

Guest host Khloe Kardashian

30 min

Mary McCormack Hosts, Allison Janney

Guest host Mary McCormack

30 min

Minnie Driver

Minnie Driver is interviewed.

30 min

Emily Mortimer

Chelsea chats with Emily Mortimer about the HBO comedy series "Doll & Em."

30 min

Adam Levine

Adam Levine is interviewed.

30 min

Tyler Perry

A pastor thinks the movie "Frozen" has a gay agenda, Steven Tyler is allegedly dating his younger assistant, passengers on a Carnival Cruise want lifetime retribution, and from "Tyler Perry's Single Moms Club" Tyler Perry is here.

30 min

Adam Carolla

L.A had an earth quake this morning, the Malaysian airplane is still missing, Guinness beer pulls out of Saint Patrick's Day Parade, and from "Catch a Contractor" Adam Carolla is here.

30 min

Theo James

The Pope refused to meet with Russell Crowe, Billy D Williams performed on "Dancing With The Stars", the couple from "Little Couple, Big World" are separating and from "Divergent" Theo James is here.

30 min

Geoff Stults

George Clooney has a new girlfriend, John Mayor is sueing Charlie Sheen's friend, The Duke porn star is getting rich, and from "Enlisted" Geoff Stults is here.

30 min

Shaun White

Johnny Weir and his husband split up, Selfies are causing a rise in plastic surgery, Is Malaysian Flight 370 somewhere off the coast of Australia, and snowboard champion Shaun White is here.

30 min

Drew Brees

Drew Brees is interviewed.

30 min

Jayma Mays

Jayma Mays is interviewed.

30 min

Rick Ross

Rapper Rick Ross is interviewed.

30 min

Bradley Trevor Greive

Bradley Trevor Greive stops by with cute baby animals.

30 min

Demián Bichir

Demián Bichir.

30 min

Mark Cuban

Mark Cuban is interviewed.

30 min

Don Cheadle

Don Cheadle is interviewed.

30 min

Mindy Kaling

Mindy Kaling is interviewed.

30 min

Jamie Foxx

Jamie Foxx is interviewed. Also: John Caparulo, Beth Stelling and Brad Wollack appear on the panel.

30 min

Sebastian Stan

Sebastian Stan chats about his role in "Captain America: The Winter Soldier." On the panel: Kerri Kenney-Silver; Dustin Ybarra; and Heather McDonald.

30 min

Nikolaj Coster-Waldau

Nikolaj Coster-Waldau is interviewed.

30 min

Amy Schumer

Comedian Amy Schumer is interviewed. On the panel: April Richardson; Sarah Colonna; and Ross Mathews.

30 min

Marlon Wayans

Marlon Wayans is interviewed.

30 min

Ellie Goulding

Singer-songwriter Ellie Goulding is interviewed. On the panel: Bobby Lee; Whitney Cummings; and Julian McCullough.

30 min

Brooklyn Decker

Brooklyn Decker is interviewed. On the panel: Michael Yo; Loni Love; and Matt Braunger.

30 min

Khloé Kardashian Hosts, Bob Saget

Guest host Khloe Kardashian

30 min

T.J. Miller Hosts, Wiz Khalifa

Guest host T.J. Miller

30 min

Loni Love Hosts, Mekhi Phifer

Guest hosts Loni Love

30 min

Mary McCormack Hosts, Ian Somerhalder

Guest host Mary McCormack

30 min

Giuliana & Bill Rancic

Giuliana and Bill Rancic are interviewed.

30 min

Hugh Dancy

Hugh Dancy ("Hannibal") is on the guest list.

30 min

Helen Hunt

Helen Hunt discusses her role in the film "Decoding Annie Parker."

30 min

Tyler Glenn

Neon Trees' frontman Tyler Glenn is interviewed.

30 min

2 Chainz

Rapper 2 Chainz is interviewed. On the panel: Julian McCullough; Brad Wollack; and Liz Carey.

30 min

Jane Lynch

Jane Lynch is interviewed. On the panel: Chris Franjola; April Richardson; Gary Valentine.

30 min

Arianna Huffington

Arianna Huffington is interviewed. On the panel: Jen Kirkman; Kevin Christy; and Josh Wolf.

30 min

Dave Franco

Dave Franco is interviewed. On the panel: Nick Thune; Ian Karmel; Heather McDonald.

30 min

Connie Britton

Connie Britton is interviewed.

30 min

Sandra Oh

Sandra Oh is interviewed.

30 min

Jason Priestley

Jason Priestley chats about his memoir.

30 min

Edie Falco

"Nurse Jackie" star Edie Falco is on the guest list.

30 min

Evan Peters

Evan Peters is on the guest list. On the panel: Ron Funches, Sarah Tiana and Brad Wollack.

30 min

Iggy Azalea

Australian rapper Iggy Azalea is interviewed. On the panel: Michael Yo; Bobby Lee; and Jo Koy.

30 min

Charlize Theron

Charlize Theron is interviewed.

30 min

Drew Barrymore & Adam Sandler

Drew Barrymore and Adam Sandler are interviewed.

30 min

Joel McHale

Joel McHale is interviewed.

30 min

Terry Crews

Terry Crews is interviewed.

30 min

Sarah Silverman

Sarah Silverman.

30 min

Lea Michele

Lea Michele is interviewed.

30 min

Kelly Osbourne

Kelly Osbourne is on the guest list.

30 min

Giovanni Ribisi

Giovanni Ribisi is interviewed. On the panel: Jeff Wild, Natasha Leggero and Josh Wolf.

30 min

Austin Mahone

Singer Austin Mahone is interviewed.

30 min

Colin Hanks

Colin Hanks is interviewed.

30 min

Lena Headey

Lena Headey is interviewed.

30 min

Channing Tatum

Chelsea chats with Channing Tatum.

30 min

Jenny Slate

Jenny Slate chats about her movie "Obvious Child." On the panel: Liza Treyger; Jen Kirkman; Julian McCullough.

30 min

Rob Riggle

Rob Riggle is interviewed. On the panel: Moshe Kasher; Fortune Feimster; and Bobby Lee.

30 min

Jason Biggs

Jason Biggs ("Orange Is the New Black") is interviewed.

30 min

Little Women: LA

The cast of the Lifetime reality series "Little Women: LA" are on the guest list. Panelists include Greg Fitzsimmons, Sarah Tiana and Julian McCullough.

30 min

Laverne Cox

Laverne Cox ("Orange Is the New Black"). On the panel: Chris Franjola; Michael Yo; Josh Wolf.

30 min

Meagan Good

Meagan Good appears in support of her movie "Think Like a Man Too." Also: Ben Gleib, Fortune Feimster and Ryan Stout are on the panel.

30 min

Kevin Hart

Kevin Hart is interviewed.

30 min

Jenna Dewan-Tatum

Jenna Dewan-Tatum chats about Season 2 of her Lifetime drama "Witches of East End."

30 min

Gabriel Iglesias

Comedian Gabriel Iglesias is on the guest list.

30 min

Chris Rock

Chris Rock is interviewed. On the panel: Brody Stevens; April Richardson; and Jo Koy.

30 min

Eric Bana

Eric Bana is interviewed about his starring role in the thriller "Deliver Us From Evil."

30 min

Melissa McCarthy

Melissa McCarthy is interviewed. On the panel: Jeff Wild; Loni Love; Brad Wollack.

30 min

Susan Sarandon

Susan Sarandon is interviewed. On the panel: Chris Franjola; Arden Myrin; Kurt Braunohler.

30 min

Ben Falcone

Bel Falcone is interviewed.

30 min

Chrissy Teigen

Model Chrissy Teigen is interviewed. On the panel: Josh Wolf; Loni Love; Gary Valentine.

30 min

Dane Cook

Dane Cook is on the guest list. On the panel: Ben Gleib; Bobby Lee; Ross Mathews.

30 min

Cameron Diaz

Cameron Diaz is interviewed. On the panel: Mary McCormack; Whitney Cummings; Julian McCullough.

30 min

Dean Norris

Dean Norris ("Under the Dome") is interviewed.

30 min

Lela Loren

Lela Loren is interviewed.

30 min

Frank Grillo

Frank Grillo, star of "The Purge: Anarchy," is interviewed.

30 min

TBA

30 min

John C. Reilly

John C. Reilly is interviewed.

30 min

Kelsey Grammer

Kelsey Grammer is interviewed.

30 min

Chris Pratt

Chris Pratt is interviewed.

30 min

TBA

30 min

Jake Owen

Country music artist Jake Owen is on the guest list.

30 min

Ethan Hawke

Ethan Hawke is interviewed.

30 min

Chandler Parsons

NBA player Chandler Parsons.

30 min

Megan Fox

Megan Fox is interviewed.

30 min

Liv Tyler

Liv Tyler ("The Leftovers") is interviewed.

30 min

Live Finale

In her opening monologue, host Chelsea Handler talks about what she did today at the studio on this the last day of the show, including the last communal shower she had in the Chelsea Lately shower facility. Chelsea and Chuy bring on her current stable of round table regulars. What Chelsea believes is going to be three of her closest celebrity friends, Mary McCormack - her best friend - Jennifer Aniston, and Sandra Bullock, providing a gracious send-off ends up being what they hope will be more useful for Chelsea's life. Chelsea's ex-lover 50 Cent and G-Unit perform their new single, "Watch Me". Chuy, via a prepared video, talks about what this show and Chelsea have meant to him. Miley Cyrus, in tribute to it being the last show, performs the pop classic, "It's Over". And many of Chelsea's musical friends, and some non-musical friends, help her serenade E!, to who she is grateful for the past seven years.

30 min