Late Night with Conan O'Brien Season 15, Episode 115: Seth MacFarlane, Carlos Mencia, MGMT

David Duchovny, Tim Gunn, Kevin Brennan

David Duchovny, Tim Gunn, Kevin Brennan appear in this episode.

45 min

Clive Owen, Alan Alda, Dinosaur Jr.

45 min

Will Arnett, Terry Crews, Patti Scialfa

Will Arnett, Terry Crews, Patti Scialfa appear in this episode.

45 min

Jeff Garlin, Nicholas Art, Hot Hot Heat

45 min

Paul Giamatti, Alyson Hannigan, Bad Religion

Paul Giamatti, Alyson Hannigan, Bad Religion appear in this episode.

45 min

Richard Gere, Seann William Scott, The Chesterfield Kings

45 min

Mary-Kate Olsen, Wayne Brady, Lyle Lovett

Mary-Kate Olsen, Wayne Brady, Lyle Lovett appear in this episode.

45 min

Billy Bob Thornton, Sen. Chris Dodd, Kenny Chesney

45 min

Patricia Heaton, Tiki Barber, The Used

Patricia Heaton, Tiki Barber, The Used appear in this episode.

45 min

Morgan Freeman, Cheryl Hines, KT Turnstall

Morgan Freeman, Cheryl Hines, KT Turnstall appear in this episode.

45 min

Kelsey Grammer, Aries Spears, James Blunt

45 min

Brad Garrett, Joy Behar, Rogue Wave

45 min

Terrence Howard, Simon Pegg, Mystery

45 min

Meredith Vieira, Steven Wright, Ben Harper & the Innocent Criminals

Tonight, Conan's guests are The Today Show's Meredith Vieira, comedian Steven Wright, and musical guest Ben Harper & the Innocent Criminals. Plus, Conan's book club.

45 min

Bob Costas, Jim Gaffigan, Rilo Kiley

45 min

Jamie Foxx, Heather Graham, Mike Birgbiglia

Tonight on Conan, actor Jamie Foxx (The Kingdom), actress Heather Graham and comedian Mike Birbiglia. Plus, another Telemundo moment with Conan.

45 min

Ted Danson, Patton Oswalt, Devendra Banhart

45 min

Dwayne "The Rock" Johnson, Ed Helms, Bjork

Tonight Conan sits down with actor/pro-wrestler Dwayne "The Rock" Johnson (The Game Plan), actor Ed Helms (The Office) and alt-musician Bjork. Plus, "In the Year 2000" with The Rock.

45 min

Seth Meyers, Bret Michaels, Jose Gonzalez

45 min

Jerry O'Connell, Ken Burns, VHS or Beta

45 min

Ted Koppel, Jason Schwartzman, Dana Gould

45 min

Tina Fey, Kenneth Branagh, Ani DiFranco

45 min

Snoop Dogg, Connie Britton, Bloc Party

45 min

Jennifer Connelly, Fred Willard, Animal Collective

45 min

Joaquin Phoenix, Jim Gaffigan, Paramore

45 min

Mark Wahlberg, Michael Strahan, The Black Lips

45 min

Tracy Morgan, Emile Hirsch, A.J. Jacobs

45 min

Jon Bon Jovi, Eva Mendes, Klaxons

Jon Bon Jovi, Eva Mendes, Klaxons are guests in this episode.

45 min

Anderson Cooper, Paget Brewster, Fionn Regan

45 min

Jake Gyllenhaal, Christina Hendricks, Ghostland Observatory

45 min

Anthony Hopkins, Joe Buck, Mute Math

45 min

John Cusack, James Lipton, Spoon

45 min

Josh Harnett, Jack McBrayer, Brother Ali

45 min

Charles Barkley, William Baldwin, Seether

45 min

Ethan Hawke, Susie Essman, Zappa Plays Zappa

45 min

Brian Williams, Roger Daltrey, Manchester Orchestra

45 min

Dane Cook, Emily Mortimer, Slash

45 min

Jerry Seinfeld, David Ortiz, Sondre Lerche

45 min

Bob Saget, Dwayne Perkins, Robert Gordon & Chris Spedding

45 min

Megan Mullally, Fonzworth Bentley, Kid Rock

45 min

Bill Maher, Jim Cramer, Mike Destefano

45 min

Hulk Hogan, Regina Hall, Nicole Atkins & the Sea

45 min

Donald Trump, Irina Markova and her performing dogs, Sia

45 min

Ice Cube, Dr. Drew Pinsky, Marah

45 min

Howie Mandel, Leigh Killian, Kate Nash

45 min

Brian Williams, David Wondrich, Doyle & Debbie

Conan welcomes NBC news anchor Brian Williams, mixologist David Wondrich and Country Western act Doyle and Debbie.

45 min

Lester Holt, Sue Johanson, Ingrid Michaelson

Tonight Conan chats with NBC's weekend anchor Lester Holt, 70+ year old sex educator Sue Johanson and musical guest Ingrid Michaelson.

45 min

Tom Brokaw, Anthony Jeselnik, Bell X1

Bell X1 performs "Rocky Took A Lover" from the album Flock.

45 min

Pink, Lou Dobbs, Bettye LaVette

45 min

Chazz Palminteri, Erin Burnett, Louis XIV

45 min

Bret Michaels, Antonio Pierce, Lisa Loeb

45 min

Jim Gaffigan, Chuck Liddell, Joe Nichols

45 min

David Gregory, Travis Pastrana, Kate Walsh

45 min

Jeff Corwin, Colin Hanks, Matt Nathanson

45 min

Dr. Phil McGraw, David Borgenicht, Les Savy Fav

Les Savy Fav perfoms "Patty Lee" from the album Let's Stay Friends.

45 min

Shawn Thayer, Ingrid Backstrom, The Blind Boys of Alabama

45 min

Ann Curry, Mike Epps, OneRepublic

45 min

Michael Strahan, Sarah Bolger, Sheryl Crow

45 min

The Great Throwdini, Donny Deutsch, The Dillinger Escape Plan

45 min

Izabel Goulart, Len Berman, Nada Surf

45 min

Professor Peter H. Fisher, Dr. Bob Arnot, Eric Lindell

45 min

Carson Kressley, Jim DeRogatis & Greg Kot, Catherine Russell

45 min

Jim Cramer, José Andrés, Band of Horses

45 min

Matt Lauer, Ryan Reynolds, Simple Plan

45 min

Martin Short, Ray Allen, The Kooks

45 min

Neil Patrick Harris, Daniella Sarahyba, Yeasayer

45 min

Larry the Cable Guy, Tim Gunn, Jim Lauderdale

45 min

Anderson Cooper, Bill Hader, Jake Shimabukuro

45 min

Randy Jackson, Artie Lange, The Whigs

Tonight's guests are Randy Jackson, Artie Lange, The Whigs.

45 min

Barbara Walters, Wladimir Klitschko, Black Mountain

45 min

Nathan Lane, Michel Gondry, Secondhand Serenade

45 min

Will Arnett, Flavor Flav, Super Furry Animals

Tonight, Conan's guests are Will Arnett, Flavor Flav and Super Furry Animals.

45 min

Will Ferrell, Rashida Jones, tae kwon do expert Fred Simmons

45 min

Tom Arnold, Todd Barry, Georgie James

45 min

Natalie Portman, Robert Schimmel, James Blunt

45 min

Christina Ricci, Jason Sudeikis, Shooter Jennings

Tonight's guests are Christina Ricci, Jason Sudeikis, Shooter Jennings.

45 min

Paul Giamatti, Mark 'Dr. Bugs' Moffett, Jaymay

45 min

Jonah Hill, John Tesh, Drive-By Truckers

45 min

Snoop Dogg, Carson Daly

45 min

Meredith Vieira, Harland Williams, Keith Robinson

Tonight's guests are Meredith Vieira, Harland Williams and Keith Robinson.

45 min

Frank Caliendo, Cheryl Hines, The Bad Plus

Tonight's guests are Frank Caliendo, Cheryl Hines and The Bad Plus.

45 min

Martha Stewart, Lance Krall, Billy Bragg

Tonight's guests are Martha Stewart, Lance Krall and Billy Bragg.

45 min

Ice-T, Brian Posehn, Stars

Tonight's guests are Ice-T, Brian Posehn and Stars.

45 min

Tracy Morgan, Chris Hansen, Paul Thorn

Tonight's guests are Tracy Morgan, Chris Hansen and Paul Thorn.

45 min

David Schwimmer, Drake Bell, Yael Naim

Tonight's guests are David Schwimmer, Drake Bell and Yael Naim.

45 min

Ryan Phillippe, Big Show, JB Smooth

45 min

Bob Costas, Marc Maron, Moby

Tonight's guests are Bob Costas, Marc Maron and Moby.

45 min

Helen Mirren, yodeler Wylie Gustafson, Carbon/Silicon

Tonight's guests are Helen Mirren, Wylie Gustafson and Carbon/Silicon

45 min

John Leguizamo, George Takei, The Bravery

Tonight's guests are John Leguizamo, George Takei and The Bravery.

45 min

John Krasinski, Bode Miller, Cobra Starship

Tonight's guests are John Krasinski, Olympian Bode Miller and Cobra Starship.

45 min

Christina Applegate, Lewis Black, Stephen Curry

Tonight's guests are Christina Applegate, Lewis Black and Stephen Curry.

45 min

George Wendt, Howard Bach, Hot Chip

Tonight's guests are George Wendt, Olympic badminton player Howard Bach and musical guest, Hot Chip.

45 min

Jarod Miller, David Gregory, John Oliver

Tonight's guests are animal expert Jarod Miller, David Gregory and comedian, John Oliver.

45 min

Eddie Izzard, Morgan Spurlock, Tapes 'N Tapes

Tonight's guests are Eddie Izzard, Morgan Spurlock and musical guest, Tapes 'N Tapes.

45 min

Sarah Jessica Parker, Eddie Izzard, They Might Be Giants

Tonight's guests are Sarah Jessica Parker, Eddie Izzard and They Might Be Giants.

45 min

Patrick Stewart, Oliver Hudson, A.A. Bondy

Tonight's guests are Patrick Stewart, Oliver Hudson and musical guest, A.A. Bondy.

45 min

Rachael Ray, Kal Penn, Grizzly Bear

Tonight's guests are Rachael Ray, Kal Penn and musical guest, Grizzly Bear.

45 min

Andy Richter, Jennifer Esposito, She + Him

Tonight's guests are Andy Richter, Jennifer Esposito and musical guest, She + Him.

45 min

Seth Green, Peter Greenberg, Radiohead

Tonight's guests are Seth Green, Peter Greenberg and musical guest, Radiohead.

45 min

Amy Poehler, Danica Patrick, Dave Attell

Tonight's guests are SATURDAY NIGHT LIVE's Amy Poehler, Danica Patrick and comedian, Dave Attell.

45 min

Tina Fey, Fred Willard, Say Anything

Tonight's guests are "30 Rock" star Tina Fey, actor Fred Willard, and musical guest Say Anything.

45 min

Marisa Tomei, Anthony Anderson, Santogold

Tonight's guests are Marisa Tomei, Anthony Anderson and musical guest, Santogold.

45 min

Jeff Garlin, Dax Shepard, The Kills

Tonight's guests are Jeff Garlin, Dax Shepard and musical guest, The Kills.

45 min

Gordon Ramsay, Rob Corddry, Feist

Tonight's guests are celebrity chef Gordon Ramsay, Rob Corddry and musical guest, Feist.

45 min

Sigourney Weaver, Darrell Hammond, Was (Not Was)

Tonight's guests are Sigourney Weaver, Darrell Hammond and musical guest, Was (Not Was).

45 min

Matthew Broderick, Michelle Monaghan, Brian Turner

Tonight's guests are Matthew Broderick, Michelle Monaghan and the captain of the Kansas City Space Pirates, Brian Turner.

45 min

Patricia Heaton, Katt Williams, Thrice

Tonight's guests are Patricia Heaton, Katt Williams and musical guest, Thrice.

45 min

Jason Lee, Eva Amurri, Galactic

Tonight's guests are Jason Lee, Eva Amurri and musical guest, Galactic.

45 min

Liam Neeson, B.J. Novak, The Duke Spirit

Tonight's guests are Liam Neeson, B.J. Novak and musical guest, The Duke Spirit.

45 min

Emile Hirsch, Terrell Owens, Craig Baldo

Tonight's guests are Emile Hirsch, Terrell Owens and comedian, Craig Baldo.

45 min

Seth Meyers, Sophia Bush, Tokio Hotel

Tonight's guests are "SNL's" Seth Meyers, "One Tree Hill's" Sophia Bush andmusical guest, Tokio Hotel.

45 min

Jimmy Fallon, William Shatner, Gary Vaynerchuk

Tonight's guests are recently announced as new "Late Night" host Jimmy Fallon, "Boston Legal" William Shatner, and wine expert Gary Vaynerchuk.

45 min

Steve Carell, Alyson Hannigan, Duffy

Tonight's guests are "The Office" Steve Carell, "How I Met Your Mother" Alyson Hannigan, and musical guest Duffy.

45 min

Brian Williams, Leighton Meester, The Black Keys

Tonight's guests are "NBC Nightly News" anchor Brian Williams, "Gossip Girl" Leignton Meester, and musical guest The Black Keys.

45 min

Alan Alda, John Cena, Everest

Tonight's guests are Alan Alda, WWE Pro wrestler John Cena, and musical guest Everest.

45 min

Kevin Nealon, Mary McCormack, DeVotchKa

Tonight's guests are comedian Kevin Nealon, actress Mary McCormack, and musical guest DeVotchKa.

45 min

Denis Leary, Anthony Bourdain, Mates of State

45 min

Harrison Ford, Eric McCormack, Atmosphere

Tonight's guests are Harrison Ford, Eric McCormack and musical guest, Atmosphere.

45 min

Kevin Spacey, Cynthia Nixon, Brian Kiley

Tonight's guests are Kevin Spacey, Cynthia Nixon and comedian, Brian Kiley.

45 min

Kristin Davis, Ira Glass, Ryan Bingham

Tonight's guests are Kristin Davis, Ira Glass and musical guest, Ryan Bingham.

45 min

The Strike Beard Show

This episode features clips from when the show returned from the WGA strike at the beginning of the '08 calendar year.

45 min

Jon Bon Jovi, Eva Mendes

45 min

Seann William Scott, Tim Meadows, The Raconteurs

Tonight's guests are actor Seann William Scott, actor Tim Meadows, and musical guest The Raconteurs.

45 min

Colin Firth, Hugh Rowland, Jackie Greene

Tonight's guests are actor Colin Firth, actor Hugh Rowland, and musical guest Jackie Greene.

45 min

Adam Sandler, Werner Herzog, Jewel

Tonight's guests are actor Adam Sandler, actor Werner Herzog, and musical guest Jewel.

45 min

Wanda Sykes, Emmanuelle Chriqui, Lewis Black

Tonight's guests are actress Wanda Sykes, actress Emmanuelle Chriqui, and comedian Lewis Black.

45 min

Kim Cattrall, Matt Taibbi, Lightspeed Champion

Tonight's guests are actress Kim Cattrall, author Matt Taibbi, and musical guest Lightspeed Champion.

45 min

Kate Hudson, Robert Smigel, James Hunter

Tonight's guests are actress Kate Hudson, actor Robert Smigel, and musical guest James Hunter

45 min

Jeff Corwin, Mario Lopez, Jamie Lidell

Tonight's guests are actor Jeff Corwin, actor Mario Lopez, and musical guest Jamie Lidell.

45 min

Mark Wahlberg, Louis C.K., Sharon Jones and The Dap-Kings

Tonight's guests are actor Mark Wahlberg, actor Louis C.K., and musical guest Sharon Jones and The Dap-Kings.

45 min

Randy Jackson, Piper Perabo, Forever the Sickest Kids

Tonight's guests are American Idol's Judge Randy Jackson, actress Piper Perabo, and musical guest Forever the Sickest Kids.

45 min

Michael Strahan, D.L. Hughley, Brian Scolaro

Tonight's guests are NY Giants' Michael Strahan, comedian D.L. Hughley, and comedian Brian Scolaro.

45 min

Ann Curry, Mario Batali, The Lordz

Tonight's guests are The Today Show's Ann Curry, Chef Mario Batali, and musical guest The Lordz.

45 min

Megan Mullally, Brittany Snow, Detroit Octane

Tonight's guests are actress Megan Mullally, actress Brittany Snow, and musical guest Detroit Octane.

45 min

Mike Myers, Jordana Spiro, Dolphina

Tonight's guests are actor Mike Myers, actress Jordana Spiro, and belly dancer Dolphina.

45 min

Anne Hathaway, Romany Malco, My Morning Jacket

Tonight's guests are actress Anne Hathaway, actor Romany Malco, and musical guest My Morning Jacket.

45 min

Jason Bateman, Masi Oka, Alejandro Escovedo

Tonight's guests are actor Jason Bateman, actor Masi Oka, and musical guest Alejandro Escovedo.

45 min

Ted Koppel, Emily Mortimer, Steel Train

Tonight's guests are journalist Ted Koppel, actress Emily Mortimer, and musical guest Steel Train.

45 min

Selma Blair, Sig Hansen, Little Jackie

Tonight's guests are actress Selma Blair, Sig Hansen, and musical guest Little Jackie.

45 min

Kyra Sedgwick, Jim Cramer, Joe Cocker

Tonight's guests are actress Kyra Sedgwick, Mad Money's Jim Cramer, and musical guest Joe Cocker.

45 min

Al Roker, Paul Pierce, Pilobolus

45 min

Sean Hayes, Ed Helms, Tom Papa

45 min

Gary Oldman, Joe Buck, Kenny Chesney

45 min

Heidi Klum, Joel McHale, Daryl Hall & K.T. Tunstall

45 min

Seth Green, Russell Brand, Eugene Mirman

45 min

Aaron Eckhart, Caroline Rhea, Dr. Dog

45 min

Senator John McCain and The Steeldrivers

Tonight's guests include presumptive Republican Presidential nominee, Senator John McCain (R-Arizona). The Steeldrivers perform.

45 min

Carson Kressley, Keke Palmer, The Ting Tings

Tonight's guests include Kelsey Grammer and Keke Palmer. The Ting Tings perform.

45 min

Jason Sudeikis, Dr. Wladimir

Tonight's guests include Jason Sudekiss and Dr. Wladimir "Steelhammer" Klitschko. Rose Hill Drive performs.

45 min

Kevin Costner, Maria Bello, Yuto Miyazawa & Gogol Bordello

45 min

Nathan Lane, Dylan Ratigan, Missy Higgins

45 min

Brendan Fraser, Steve Schirripa, The Airborne Toxic Event

45 min

America Ferrera, Judd Apatow, Dwayne Perkins

45 min

Seth Meyers, Sharon Osbourne, N*E*R*D

45 min

Javier Bardem, Danny McBride, The B-52s

45 min

Seth Rogen, Philippe Petit, Al Green

45 min

Kiefer Sutherland, Jim Gaffigan, Mason Jennings

45 min

Daniel Radcliffe, Steve Coogan, The Hold Steady

Daniel Radcliffe, English star of the Harry Potter series of movies, is the guest star along English comedian and actor Steve Coogan; with Musical guest The Hold Steady.

45 min

Vin Diesel, Dave Attell, The Virgins

45 min

Tiger Woods, Vanessa Minnillo, Jimmy Carr

45 min

Aaron Peirsol, Anthony Anderson, Lykke Li

Tonight's guests include Aaron Peirsol and Anthony Anderson. Lykke Li performs.

45 min

Bob Costas, Sophia Bush, The Spring Standards

45 min