The Ellen DeGeneres Show Season 6, Episode 115: Neil Patrick Harris, Kaley Cuoco

Episode 1

45 min

Episode 18

Nicollette Sheridan/The All-American Rejects

45 min

George Clooney/Kiefer Sutherland/T.I.

45 min

Amy Poehler, James Morrison

45 min

Joey Fatone, O.A.R.

45 min

Ted Danson, Ernie Bjorkman

45 min

Kevin Nealon, Chris Harrison

45 min

Alyson Hannigan, Brandon Wilson

45 min

Heidi Klum, Justin Long, Marco Borges

45 min

Josh Brolin, Pink with Butch Walker

45 min

Penelope Cruz, Dylan and Cole Sprouse, Q-Tip

45 min

Jennifer Aniston, Stevie Wonder

45 min

John Mayer, Josh Groban, Lady Antebellum, Chester Pitts, Ephraim Salaam

45 min

Amy Brenneman, Jason Mraz and Colbie Caillat

45 min

Mel B, Eric Dane, Robin Tunney, Melinda Doolittle

45 min

Steve Harvey, Kurt Warner, Dr. Neil Shaw

45 min

John Legend, Jerry O'Connell

45 min

Simon Baker, Miranda Cosgrove

45 min

The Jonas Brothers, Mel B

45 min

Naomi Watts, Lily Allen

45 min

Jeff Probst, Nick Carter

45 min

George Lopez, Bar Refaeli

45 min

Meredith Vieira, Olivia Wilde

45 min

Richard Simmons, Serena Williams, Raphael Saadiq

45 min

Denise Richards, Chyler Leigh, Fabio Viviani

45 min

Mario Lopez, the Bird and the Bee

45 min

David Arquette, Fall Out Boy

45 min

Judge Judy Sheindlin, Bret Michaels, Matt Nathanson

45 min

Eric McCormack, Chris Harrison, Anthony LaPaglia, the Fray

45 min

"The Bachelor" runner-up Melissa Rycroft, Kym Douglas

45 min

Jason Mesnick and Molly Malaney, Steve Spangler

45 min

Paris Hilton

45 min

Carla Gugino, Sean "Diddy" Combs, Taylor Hicks

45 min

Carol Burnett, Taylor Hicks

45 min

Felicity Huffman, Rascal Flatts

45 min

Dwayne "The Rock" Johnson, Elle Fanning

45 min

Portia de Rossi, "American Idol" castoffs Jorge Nunez and Jasmine Murray

45 min

Julia Louis-Dreyfus, Andy Samberg

45 min

Zach Braff, Jenna Fischer

45 min

Anderson Cooper, Katy Perry

45 min

Paul Rudd, Gavin Rossdale, 7-year-old golfer Brett Sodetz

45 min

Noah Wyle, "American Idol" castoff Alexis Grace

45 min

Kara DioGuardi, M.C. Hammer

45 min

John Stamos, Emily Blunt

45 min

Jennifer Hudson

45 min

Reese Witherspoon, Bobby Flay

45 min

David Spade, Gilles Marini and Cheryl Burke

45 min

Halle Berry, Flo Rida

45 min

Christina Applegate, Keith Urban

45 min

Howie Mandel, Ben Mckenzie

45 min

Marilu Henner, Lil' Kim and Derek Hough, Martina McBride

45 min

Patricia Arquette, Wayne Hoffman, "Dancing With the Stars" castoff David Alan Grier, Rascal Flatts

45 min

Jenny McCarthy, Mary McCormack, Natasha Bedingfield

45 min

Zac Efron, Demi Lovato

45 min

Jessica Lange, Melissa Rycroft and Tony Dovolani, Ludacris and Jesse McCartney

45 min

Drew Barrymore, Barry Watson, the Pussycat Dolls

45 min

Leslie Mann, Rashida Jones, Pussycat Dolls

45 min

Jimmy Kimmel, Marilyn Milian, Brett Dennen, 7-year-old break-dancer Angelo Baligad

45 min

Jennifer Love Hewitt, Chicago

45 min

Lindsay Lohan, Alec Greven, Prince

45 min

Matthew Perry, Leighton Meester

45 min

Kristin Chenoweth, "American Idol" castoffs Anoop Desai and Lil Rounds

45 min

Kate Walsh, Dierks Bentley, child solar-system expert Brandt Bickford

45 min

Michael Douglas, Faryl Smith

45 min

Ryan Reynolds, 7-year-old piano prodigy Emily Bear

45 min

Matthew McConaughey

45 min

Heidi Klum, Annie Duke, "American Idol" castoff Matt Giraud

45 min

Simon Cowell, Zachary Quinto, the Black Eyed Peas

45 min

Hugh Jackman, Chris Pine

45 min

Vanessa Hudgens, 11-year-old sport stacker Steven Purugganan, Kym Douglas

45 min

Ryan Seacrest, Alison Sweeney

45 min

Jon Cryer, "American Idol" castoff Allison Iraheta, Alison Sweeney

45 min

Matthew Fox, Julianne Moore, Lady GaGa

45 min

Jay Leno, Ciara

45 min

Anderson Cooper, Kelly Clarkson

45 min

Ewan McGregor, the winner of "The Biggest Loser", Pink

45 min

Jamie Foxx, Marisa Miller, piano prodigy Umi Garrett

45 min

George Lopez, No Doubt

45 min

Ben Stiller, David Cook

45 min

Kevin Nealon, Tamar Geller, Michael Johns

45 min

Queen Latifah, Wayne Dyer, Rob Thomas

45 min

Steve Martin

45 min

Mandy Moore, Kris Allen

45 min

Jessica Biel, Kathy Freston, Kellie Pickler

45 min